Inflammation Helps Heal Muscle Injury? Did I read that Right?

Conventional wisdom says to medical professionals: control inflammation to promote muscle healing. A new study from the Cleveland Clinic questions this convention. Lan Zhou, M.D., Ph.D., and colleagues at the Cleveland Clinic found that inflammatory cells (macrophages) in acute muscle injury produce a high level of an insulin-like growth factor-1 (IGF-1) which increases the rate of muscle regeneration. Here is the abstract and here is a description of the study from Science Daily.

Bottom-line: “For wounds to heal we need controlled inflammation, not too much, and not too little.” That’s the advice of Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal where the article was published.


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s